Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-3-(Piperidin-2-yl)pyridine, is researched, Molecular C10H14N2, CAS is 494-52-0, about Thermal desorption-cooled injection system-gas chromatography-mass spectrometry for simultaneous determination of seven kinds of alkaloids and nine kinds of flavor compounds in cigarette.Name: (S)-3-(Piperidin-2-yl)pyridine.
A novel method for determination of seven kinds of alkaloids (isoquinoline, nicotine, 3-(2-pyrrolidinyl) pyridine nornicotine, myosmine, β-nicotyrine, Anabasine, 2,3′-bipyridine, and anabaseine) and nine kinds of flavor compounds (hydrocoumarin, vanillin, coumadin, Et vanillin, Me vanillin, 7-Me coumarin, 7-methoxycoumarin, 7-ethoxy-4-methylcoumarin, and pyranocoumarin) in cigarette by thermal desorption-cooled injection system coupled with gas chromatog.-mass spectrometry (TDU-CIS-GC-MS) was developed. By optimizing the conditions such as TDU (time, temperature, and flow rate of helium gas), CIS temperature, vent time and purge time, the cigarette alkaloid compound could be completely thermal desorption, and the volatile alkaloids and coumarin substances were enriched using the cold injection system. A DB-5 MS chromatog. column was used for separation, and a matrix curve external label method was used to quantify the matrix effect under the selected ion monitoring mode (SIM). The results showed that the linear range of 7 kinds of alkaloids and 9 kinds of flavors was 1-500 μg/L, the linear correlation coefficient (R2) was greater than 0.993, and the limits of detection (LOD) and limits of quantitation (LOQ) were 0.02-0.50 μg/kg and 0.1-2.0 μg/kg, resp. This method was simple, safe with high sensitivity and accuracy, and suitable for the determination of alkaloids and flavor compounds in cigarette, which was very important for the anal. of complex volatile trace substances in heated non-burning cigarette.
In addition to the literature in the link below, there is a lot of literature about this compound((S)-3-(Piperidin-2-yl)pyridine)Name: (S)-3-(Piperidin-2-yl)pyridine, illustrating the importance and wide applicability of this compound(494-52-0).
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI