Catalyst ligands

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2304-30-5,Tetrabutylphosphonium chloride,as a common compound, the synthetic route is as follows.

EXAMPLE 4 27.35 g of 3-methyl-3-chloro-2-(2′,2′-dichlorovinyl)-butanecarboxylic acid ethyl ester in the form of the crude solution prepared in Example 1 were dissolved in 50 ml of toluene. 2 g of tetrabutylphosphonium chloride were added and 16.8 g of 50% strength potassium hydroxide solution were then added dropwise at 0 C. The solution was subsequently stirred until it had reached room temperature and was then stirred for a further 1 hour at 35 C. It was then diluted with ice-water and rendered neutral and the organic phase was separated off and fractionated. This gave 21.9 g (92.5% of theory) of 2,2-dimethyl-3-(2′,2′-dichlorovinyl)-cyclopropanecarboxylic acid ethyl ester., 2304-30-5

2304-30-5 Tetrabutylphosphonium chloride 75311, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Bayer Aktiengesellschaft; US4217300; (1980); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

485-71-2, Cinchonidine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of (-)-cinchonidine (1.0 mmol) and benzyl bromide 3 (1.0 mmol) having sulfonamidegroup was stirred in DMF (4 mL) at 25 C for 20 h. After the reaction was completed, the reaction mixture was added dropwise to ether (50mL) with stirring. The solid precipitated was filtered,washed with ether (20 mL) and hexane (20 mL) to afford cinchonidinium salt 5

485-71-2, 485-71-2 Cinchonidine 101744, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Itsuno, Shinichi; Yamamoto, Shunya; Takata, Shohei; Tetrahedron Letters; vol. 55; 44; (2014); p. 6117 – 6120;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

10534-59-5, Tetrabutylammonium acetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Preparation of four different solutions of tetradecavanadates, VxOyALz (A = Cl- or CH3CO2-, L = (C2H5)4N+ or (C4H9)4N+), was carried out according to a modified literature procedure [31]. All chemicals were purchased from Sigma-Aldrich and used as received. Briefly, 1.5 mmol of vanadyl acetylacetonate [VO(acac)2] and 0.6 mmol of either tetraethylammonium chloride [(C2H5)4NCl], tetrabutylammonium chloride [(C4H9)4NCl], tetraethylammonium acetate [(C2H5)4N(CH3CO2)] or tetrabutylammonium acetate [(C4H9)4N(CH3CO2)] were dissolved in 50 mL of acetonitrile. 0.8 mmol of triethyl amine was then added to the initial mixtures while stirring constantly at room temperature. Following 6 h of reaction, an Oakton 10 series pH meter (calibrated using buffers of pH 4, 7 and 10 at room temperature) was used to determine the pH of the resulting brown-colored solutions. The product mixtures were de-solvated under reduced pressure using a VWR1400E vacuum oven. Recrystallization was carried out in approximately 3 mL of N,N-dimethylformamide (N,N-DMF) by heating the solution to the boiling temperature (153 C) for 10 min. Any remaining N,N-DMF was then evaporated in vacuum to obtain pure dry crystals of polyoxovanadates. A small quantity of crystals was dissolved in acetonitrile to prepare concentrated stock solutions. These stock solutions were diluted further by factors of ten or one hundred in acetonitrile prior to analysis by ESI-MS.

10534-59-5, The synthetic route of 10534-59-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Johnson, Grant E.; Al Hasan, Naila M.; Laskin, Julia; International Journal of Mass Spectrometry; vol. 354-355; (2013); p. 333 – 341;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.29841-69-8,(1S,2S)-(-)-1,2-Diphenylethylenediamine,as a common compound, the synthetic route is as follows.

A solution of sulfonyl chloride B (10 mmol) in dichloromethane (25 mL) was slowlyadded to a stirred solution of diamine A (10 mmol), NEt3 (11 mmol) in dichloromethane(25 mL). The resulting mixture was stirred for another 3 hr, washed twice with water (25mL) and dried over Na2SO4. The solvent was removed in vacuo to give a white solid C. Toa solution of D in CH2Cl2 (40 mL) was added NEt3 (11 mmol), isobutyl carbonochloridate(11 mmol) at 0 oC under stirring. After 10 min, C was added. The reaction was allowed towarm to room temperature for another 3 hr. The mixture was washed with 1 M KHSO4solution, saturated NaHCO3 solution, and brine, dried over anhydrous Na2SO4 andconcentrated to get a white solid E. Then, TFA (10 mL) was added to the CH2Cl2 (10 mL)solution of E, and stirred until the reaction finished (1 hr). The pH value of the mixture wasbrought into the range of 10-12 by the addition of 2 N NaOH solution. The aqueousphase was extracted with CH2Cl2 (3 ¡Á 30 mL). The combined organic phase was washedwith brine, dried over anhydrous Na2SO4, and concentrated and purified through flashchromatograph as a white solid F (70% yield).

29841-69-8, The synthetic route of 29841-69-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Tang, Yu; Xu, Jian; Yang, Jian; Lin, Lili; Feng, Xiaoming; Liu, Xiaohua; Chem; vol. 4; 7; (2018); p. 1658 – 1672;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

4730-54-5, 1,4,7-Triazacyclononane is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,4730-54-5

Amixture of 17 (0.448 g, 2.24 mmol), potassium carbonate (0.41 g,3.0 mmol) and TACN (0.095 g, 0.74 mmol) in acetonitrile (20 mL) wasrefluxed overnight. The mixture was then added to water (50 mL) beforeextraction with dichloromethane (3 ¡Á 50 mL). The organic extractswere washed with brine (50 mL) before being dried with magnesiumsulfate and the solvent removed in vacuo to yield a dark orange highlyviscous liquid (0.431 g, 93%). deltaH (400 MHz; CDCl3; Me4Si) 2.87 (12H,s) 3.72 (6H, s) 4.79 (6H, d, J 6.4 Hz) 5.38 (6H, m) 6.05 (3H, m) 6.15(3H, dd, J 1.4, 6.9 Hz) 6.56 (3H, dd, J 1.4, 9.2 Hz) 7.24 (3H, dd, J 6.9,9.2 Hz); deltaC (100 MHz) 55.9, 57.1, 76.7, 104.8, 120.4, 122.1, 130.5,137.9, 147.7, 159.7; (+)-ESI-MS:m/z 619.05 (M+H+); NESI: requires;m/z 619.3244, found; 619.3243 (M + H+).

4730-54-5 1,4,7-Triazacyclononane 188318, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Workman, David G.; Hunter, Michael; Dover, Lynn G.; Tetard, David; Journal of Inorganic Biochemistry; vol. 160; (2016); p. 49 – 58;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

156492-30-7, 4,7-Dibromo-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The compound 73d (5.1 g, 15.0 mmol),Phenoxazine (5.8 g, 32 mmol)Tert-butylphosphine (0.35 g, 2 mmol),Palladium acetate (0.4 g, 1.8 mmol) and cesium carbonate (19.5 g, 60 mmol) were dissolved in toluene,Under a nitrogen atmosphere,The reaction was heated under reflux for 10 hours.The solvent was evaporated in vacuo,The remaining material was stirred with pentane,filter,Purification by silica gel column chromatography,To obtain solid compound 5, (5.31 g, 9.8 mmol)Yield 65%.

156492-30-7, 156492-30-7 4,7-Dibromo-1,10-phenanthroline 11393583, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Shanghai Tianma Organic Shine Display Co., Ltd.; Tianmawei Electronic Co., Ltd.; Wang Xiangcheng; Liu Ying; Ren Hongyang; He Wei; Liu Chen; (43 pag.)CN106831743; (2017); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: The corresponding ligand (1mmol) was added to a MeCN solution (40mL) of the corresponding metal pivalate (1mmol). The resulting mixture was stirred at t=60C for 2h, filtered off, and slowly cooled to room temperature. The solution was kept at room temperature, and crystals precipitated for 6-48h. In some cases, single crystals suitable for X-ray diffraction studies were obtained after recrystallisation from MeCN (slow evaporation under reduced pressure).

1662-01-7, 1662-01-7 4,7-Diphenyl-1,10-phenanthroline 72812, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Nikolaevskii, Stanislav A.; Evstifeev, Igor S.; Kiskin, Mikhail A.; Starikova, Alyona A.; Goloveshkin, Alexander S.; Novikov, Valentin V.; Gogoleva, Natalya V.; Sidorov, Alexey A.; Eremenko, Igor L.; Polyhedron; vol. 152; (2018); p. 61 – 72;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

2304-30-5, Tetrabutylphosphonium chloride is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The same procedure described above for the preparation of [nBu4P][PtBr3(C2H4)] was adopted, except for the use of PtCl2 (100.2 mg, 0.38 mmol) and nBu4PCl (102.4 mg, 0.38 mmol), with the addition of 10 mL of dry toluene. Yield: 148.4 mg, 66%. 1H NMR (CDCl3): delta 4.48 (s + d, JPt-H = 64.3 Hz, 4H, C2H4), 2.30 (m, 8H, br, PCH2), 1.60 (m, 4, br, CH2CH2), 1.05 (m, 3, br, CH3). 31P{1H} NMR: delta 33.14. 195Pt NMR: delta -2743(quint 2JPt-H = 64 Hz). Anal. % Calcd. for C18H40Cl3PPt (M = 588.930): C, 36.71; H, 6.85. Found: 37.2; H, 6.9., 2304-30-5

As the paragraph descriping shows that 2304-30-5 is playing an increasingly important role.

Reference£º
Conference Paper; Bethegnies, Aurelien; Poli, Rinaldo; Journal of Organometallic Chemistry; vol. 730; (2013); p. 165 – 167;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.76089-77-5,Cerium(III) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

76089-77-5, Example 4The above-described ligand represented by formula (B-10) (50 mg, 0.066 mmol) and cerium trifluoromethanesulfonate (35 mg, 0.060 mmol) were charged into a flask. Then, ethanol (4 mL) was added thereto and dissolved. The mixed solution was stirred for 2.5 hours at room temperature, and then the stirring was stopped. About 4 mL of diethyl ether was added, and the resultant mixture was left to stand overnight. After that, the produced solid was collected to obtain the above-described metal complex represented by composition formula (C-10) (hereinafter, ?metal complex (C-10)?). The collected amount was 51 mg (yield 63%).Elemental analysis: Found (%) C, 44.27; H, 4.39; N, 10.30; S, 7.33. Calcd for C50H58CeF9N10O9S3 (%) C, 44.47; H, 4.33; N, 10.37; S, 7.12.The metal complex (C-10) emitted a blue color in a solid powder state and in a solution state (acetonitrile) under ultraviolet excitation (365 nm).The emission spectrum in acetonitrile had a peak at 421 nm, the emission quantum yield was 21%, and the excitation life was 73.8 ns.

76089-77-5 Cerium(III) trifluoromethanesulfonate 2733941, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; US2012/211706; (2012); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1067-33-0, Dibutyltin diacetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 7; 306 g of a residual liquid were obtained by carrying out the same method as Example 6 with the exception of using 255 g of di-n-butyl tin diacetate, and using 961 g of 3-methyl-1-butanol (Tokyo Chemical Industry Co., Ltd., Japan) instead of 2-ethyl-1-butanol. The residual liquid contained 92.7% by weight of di-n-butyl-bis(3-methylbutyloxy) tin. In addition, the low boiling point component contained 18.0% by weight of isoamyl acetate.

1067-33-0, 1067-33-0 Dibutyltin diacetate 16682740, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Shinohata, Masaaki; Miyake, Nobuhisa; US2010/292496; (2010); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI