Catalyst ligands

Abdel-Kader, Maged S.; Al-Taweel, Areej M.; El-Deeb, Kadriya S. published an article about the compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one( cas:32780-06-6,SMILESS:O=C1O[C@H](CO)CC1 ).Synthetic Route of C5H8O3. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:32780-06-6) through the article.

Bioactivity guided phytochem. study of the petroleum ether and butanol extracts of Clematis hirsuta resulted in the isolation of 12 compounds Rat paw edema as a model of acute inflammation was used to evaluate the anti-inflammatory activity of the extracts and the chromatog. fractions. Five known sterols and triterpenes namely: β-amyrin (1), lupeol (2), β-sitosterol (3), oleanolic acid (4) and stigmasterol glycoside (5) were isolated from the petroleum ether extract The n-butanol extract afforded two compounds reported for the first time from natural source: (S)-(+)-dihydro-5-(hydroxymethyl)-2(3H)-furanone (7) and (S)-(-)-5-hydroxymethyl-2(5H)-furanone (8). In addition, anemonin (6), dihydro-4-hydroxy-5-(hydroxymethyl)-2(3H)-furanone (2-deoxy-D-ribono-1,4-lactone) (9), biophenol (cimidahurin) (10), glucose (11) and sucrose (12) were also identified. The structures were determined from spectroscopic data including 1D- and 2D-NMR experiments

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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 89972-77-0, is researched, SMILESS is CC1=CC=C(C2=CC(C3=NC=CC=C3)=NC(C4=NC=CC=C4)=C2)C=C1, Molecular C22H17N3Journal, Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry called A two-component co-crystal of Cu(II) complex of p-tolyl-terpyridine, Author is Bhattacharya, Dibyendu, the main research direction is crystal structure copper tolyl terpyridine nitrate complex preparation.Computed Properties of C22H17N3.

A unique two-component co-crystal, [Cu(L)(NO3)2][Cu(L)(NO3)(CH3OH)](NO3)·H2O (L = p-tolyl-terpyridine) has been prepared in (1:1) water-methanol medium at room temperature and characterized by single-crystal x-ray diffraction anal. The compound crystallizes in the triclinic system (space group P1̅). The structure consists of two mononuclear Cu(II) moieties, one cationic and another neutral. In the asym. unit, one Cu(II) center furnishes a five-coordinated distorted square pyramidal geometry (CuN3O2), organized by three nitrogens of L ligand and one oxygen of a monodentate nitrate anion in the equatorial position and one methanol mol. in the apical position with geometry index τ5 = 0.15. The other Cu(II) center displays a four-coordinate distorted square planar geometry (CuN3O), framed by three nitrogens of ligand L and one oxygen of a monodentate nitrate anion with geometry index τ4 = 0.29 and the tetrahedral character parameter, THCDa/100 of -1.00.

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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Journal of Chemical Ecology called Bioactivity, synthesis, and chirality of the sex pheromone of currant stem girdler, Janus integer, Author is James, David G.; Petroski, Richard J.; Cosse, Allard A.; Zilkowski, Bruce W.; Bartelt, Robert J., which mentions a compound: 32780-06-6, SMILESS is O=C1O[C@H](CO)CC1, Molecular C5H8O3, Recommanded Product: 32780-06-6.

It was previously reported that females of the currant stem girdler, Janus integer Norton (Hymenoptera: Cephidae), produce a compound, (Z)-9-octadecen-4-olide (I), that is sensitively detected by the antennae of males only. These characteristics suggested a pheromonal function, and this has now been confirmed with behavioral tests. Field tests conducted during two seasons in a com. red currant field showed that synthetic racemic I is attractive to male J. integer under natural conditions. A clear dose-response was evident, with greatest numbers of girdlers caught in sticky traps baited with 10 mg of the pheromone (in rubber septa) and least in traps baited with 1 mg or less. During May 2002, 10, 5, 3, and 1 mg baited traps caught means of 41.4, 26.6, 6.7, and 2.7 males/trap/visit (3-5 day intervals), resp., with a maximum of 229 males caught in a single trap baited with 5 mg. A new synthetic method for racemic I is presented. The absolute configuration of natural I from the male sawflies was determined to be (R). The potential for using the sex pheromone of J. integer to improve management of this currant and gooseberry pest is discussed.

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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Name: (S)-3-(Piperidin-2-yl)pyridine. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (S)-3-(Piperidin-2-yl)pyridine, is researched, Molecular C10H14N2, CAS is 494-52-0, about A rapid LC-MS/MS method for simultaneous determination of nicotine and its key derivatives including hydroxylation isomers. Author is Shen, Yixiao; Zhang, Ning; Prinyawiwatkul, Witoon; Xu, Zhimin.

A rapid high pressure liquid chromatog. coupled with tandem mass spectrometry method (LC-MS/MS) was developed for simultaneously determining nicotine (NT) and its derivatives including cotinine (CT), trans-3-hydroxycotinine (HC), nornicotine (NNT), anatabine (AT), anabasine (AB) and amino ketone (4-(methylamino)-1-(3-pyridyl)1-butanone) (AK) as well as two important metabolites isomers 2-hydroxynicotine (2-HN) and 6-hydroxynicotine (6-HN) in tobacco leaves. Different from other methods, 2-HN and 6-HN isomers can be successfully separated and quantified through a combination of amide and C18 columns and optimized multiple reaction monitoring mode of tandem mass spectrometry. The limits of detections (LOD) and quantification (LOQ) of these compounds were 0.02 and 0.06 ng/mL for CT and HC, 0.05 and 0.15 ng/mL for AK and 6-HN, and 0.1 and 0.3 ng/mL for AB, NNT, AT, 2-HN and NT, resp. Their recoveries ranged from 86.1% for 2-HN to 102.2% for AK by using solvent extraction assisted with ultrasonication. The developed method was validated through determination of the compounds in different regular and genetically modified (for lowering nicotine) tobacco leaves. Conclusively, it is a robust and rapid method for simultaneous quantification of nicotine and its derivatives in tobacco products. The protocol of the method could also be applied in developing anal. method for tracking the toxic substances synthesis and metabolism in tobacco leaves or other herbal plants.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 5,6-Dihydro-2H-pyran-2-one, is researched, Molecular C5H6O2, CAS is 3393-45-1, about Electrochemically driven desaturation of carbonyl compounds.SDS of cas: 3393-45-1.

Electrochem. techniques have long been heralded for their innate sustainability as efficient methods for achieving redox reactions. Carbonyl desaturation, as a fundamental organic oxidation, is an oft-employed transformation to unlock adjacent reactivity. To date, the most reliable methods for achieving it have relied on transition metals (Pd/Cu) or stoichiometric reagents based on I, Br, Se, or S. Herein the authors report an operationally simple pathway to such structures from enol silanes and phosphates using electrons as the primary reagent. This electrochem. driven desaturation exhibits a broad scope across an array of carbonyl derivatives, is easily scalable (1-100g), and can be predictably implemented into synthetic pathways using exptl. or computationally derived NMR shifts. Mechanistic interrogation suggests a radical-based reaction pathway.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wang, Dongyue; Wang, Huifang; Li, Huanrong researched the compound: 4-(p-Tolyl)-2,2:6,2-terpyridine( cas:89972-77-0 ).Application In Synthesis of 4-(p-Tolyl)-2,2:6,2-terpyridine.They published the article 《Novel Luminescent Soft Materials of Terpyridine-Containing Ionic Liquids and Europium(III)》 about this compound( cas:89972-77-0 ) in ACS Applied Materials & Interfaces. Keywords: luminescent europium coordinated ionic liquid terpyridine functionalized imidazolium. We’ll tell you more about this compound (cas:89972-77-0).

The authors describe novel luminescent soft materials via reaction of Eu3+-coordinated carboxyl functionalized ionic liquids with terpyridine-functionalized imidazolium salts that are built from an imidazolium ring substituted on one side with a terpyridine derivative and, on the opposite side, a paraffin chain of various lengths. The obtained materials are either pastelike substances or viscous fluids, depending on the anions of the carboxyl functionalized ionic liquids The soft luminescent materials were investigated by Fourier transform IR spectroscopy (FT-IR), x-ray diffraction (XRD), thermogravimetry (TG), and luminescence spectroscopy. The soft materials show bright red emission irradiated with UV light, because of the energy transfer from terpyridine-functionalized imidazolium salts to the Eu3+ ions. The absolute quantum yields of the materials were determined and the energy transfer efficiency was estimated according to the reported method.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 89972-77-0, is researched, Molecular C22H17N3, about Crystal structure of bis{[4′-(4-tolyl)-2,2′:6’2”-terpyridine-κ3N,N’,N”][μ-5-hydroxybenzene-1,3-dicarboxylate-κ2O,O’]zinc(II)} tetrahydrate [Zn(C22H17N3)(C8H6O5)]2·4H2O, the main research direction is crystal structure zinc tolylterpyridine hydroxybenzenedicarboxylato dinuclear complex hydrate; mol structure zinc tolylterpyridine hydroxybenzenedicarboxylato dinuclear complex hydrate.Product Details of 89972-77-0.

Crystallog. data and at. coordinates are given. In the title crystal structure, each Zn(II) cation is five-coordinated by three N atoms from 4′-(4-tolyl)-2,2′ 6,2”-terpyridine and two O atoms from two 5-hydroxybenzene-1,3-dicarboxylic acid ligands forming a slightly distorted trigonal bipyramid. The distances d(Zn-N) are in the range of 2.056(4) – 2.181(4) Å, d(Zn-O) = 1.962(3) Å. The bond distances and angles are in normal ranges.

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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Computed Properties of C10H12N4. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 6-(Piperazin-1-yl)nicotinonitrile, is researched, Molecular C10H12N4, CAS is 149554-29-0, about Synthesis of new and potent analogs of anti-tuberculosis agent 5-nitrofuran-2-carboxylic acid 4-(4-benzylpiperazin-1-yl)benzylamide with improved bioavailability. Author is Tangallapally, Rajendra P.; Lee, Robin E. B.; Lenaerts, Anne J. M.; Lee, Richard E..

Previously, the lead compound 5-nitrofuran-2-carboxylic acid 4-(4-benzylpiperazin-1-yl)benzylamide was identified in our anti-tuberculosis drug discovery program. Although this compound demonstrated excellent in vitro activity, it did not meet the expected in vivo profiles due to structural features that resulted in rapid metabolic cleavage and poor absorption, which therefore limited its bioavailability. In efforts to increase the bioavailability, a new series of analogs was successfully synthesized using three modification schemes: replacement of the benzyl group on the piperazine C-ring with carbamate and urea functional groups; introduction of a nitrogen atom into the aromatic ring-B; and expansion of the ring-B to a bicyclic tetrahydroisoquinoline moiety. These modifications retained strong activity and in some case gained superior anti-tuberculosis activity, increased absorption, and serum half life.

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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Bonneau, Guillaume; Peru, Aurelien A. M.; Flourat, Amandine L.; Allais, Florent researched the compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one( cas:32780-06-6 ).Quality Control of (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one.They published the article 《Organic solvent- and catalyst-free Baeyer-Villiger oxidation of levoglucosenone and dihydrolevoglucosenone (Cyrene): a sustainable route to (S)-γ-hydroxymethyl-α,β-butenolide and (S)-γ-hydroxymethyl-γ-butyrolactone》 about this compound( cas:32780-06-6 ) in Green Chemistry. Keywords: catalyst Baeyer Villiger oxidation levoglucosenone Cyrene hydroxymethylbutenolide hydroxymethylbutyrolactone. We’ll tell you more about this compound (cas:32780-06-6).

A straightforward and sustainable route to (S)-γ-hydroxymethyl-α,β-butenolide (HBO) and (S)-γ-hydroxymethyl-α,β-butyrolactone (2H-HBO), two valuable chem. platforms for the synthesis of fine chems. such as drugs, pheromones, flavors and fragrances, has been optimized using renewable cellulose-based levoglucosenone (LGO) and Cyrene as starting materials and aqueous H2O2 as both a solvent and an oxidizing agent. Combined with short-path distillation, this procedure provides enantiopure HBO and 2H-HBO in yield as high as 72% at the kilo scale.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Ren, Mengjuan; Zhang, Mengyue; Yang, Huijuan; Shi, Hongzhi researched the compound: (S)-3-(Piperidin-2-yl)pyridine( cas:494-52-0 ).Reference of (S)-3-(Piperidin-2-yl)pyridine.They published the article 《Reducing the nicotine content of tobacco by grafting with eggplant》 about this compound( cas:494-52-0 ) in BMC Plant Biology. Keywords: tobacco eggplant grafting nicotine; Differentially expressed genes; Grafting; Nicotine content; Tobacco; Transcription factors. We’ll tell you more about this compound (cas:494-52-0).

Background: Nicotine is a stimulant and potent parasympathomimetic alkaloid that accounts for 96-98% of alkaloid content. A reduction in the amount of nicotine in cigarettes to achieve a non-addictive level is necessary. We investigated whether replacing tobacco root with eggplant by grafting can restrict nicotine biosynthesis and produce tobacco leaves with ultra-low nicotine content, and analyzed the gene expression differences induced by eggplant grafting. Results: The nicotine levels of grafted tobacco leaves decreased dramatically. The contents of nornicotine, anabasine, NNN, NNK, NAT, total TSNAs and the nicotine of mainstream cigarette smoke decreased, and the contents of amino acids and the precursors of alkaloids increased in grafted tobacco. Eggplant grafting resulted in the differential expression of 440 genes. LOC107774053 had higher degrees in two PPI networks, which were regulated by LOC107802531 and LOC107828746 in the TF-target network. Conclusions: Replacing tobacco root with eggplant by grafting can restrict nicotine biosynthesis and produce tobacco leaves with ultra-low or zero nicotine content. The differential expression of LOC107774053 may be associated with eggplant grafting.

If you want to learn more about this compound((S)-3-(Piperidin-2-yl)pyridine)Reference of (S)-3-(Piperidin-2-yl)pyridine, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(494-52-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI