13910-48-0, N1-Benzylpropane-1,3-diamine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2-(4-tert-butylphenyl) -4-(methylsulfanyl) -6H,7H-pyrazolo [1,5 -aj [1,3 ,5j triazin-7 -one(75 mg, 0.239 mmol) and (3-aminopropyl)(benzyl)amine (117 mg, 0.71 mmol) were dissolved in Pyridine (1 mL). The reaction mixture was heated in a microwave at 140 C for2h. The reaction mixture was evaporated to dryness and purified by preparative HPLC method A affording the title compound as a pale yellow oil (35 mg, 34 %).?H NMR (500 MHz, Methanol-d4) 8.36 (s, 2H), 8.29 – 8.20 (m, 2H), 7.56 – 7.46(m, 2H), 7.44 -7.30 (m, 5H), 5.70 (s, 1H), 4.15 (s, 2H), 3.83 (t, I = 6.3 Hz, 2H), 3.24 -3.08 (m, 2H), 2.18 (dt, I = 14.2, 6.5 Hz, 2H), 1.37 (s, 9H). LCMS Method B: ft 2.44 mm, 100 %; m/z 432 (MH)., 13910-48-0
The synthetic route of 13910-48-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; EVOTEC INTERNATIONAL GMBH; GAMPE, Christian, M.; KAHNE, Daniel, Evan; KAHNE, Suzanne, Walker; QIAO, Yuan; EAST, Stephen; PARKES, Alastair, L.; SOUTHEY, Michelle; HUNTER, James; WHITTAKER, Mark; ARTHUIS, Martin; (359 pag.)WO2016/191658; (2016); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI