The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about Plant growth regulators and Axl and immune checkpoint inhibitors from the edible mushroom Leucopaxillus giganteus, the main research direction is Leucopaxillus lung cancer anticancer plant growth regulator Axl PDL1; Leucopaxillus giganteus ; Axl inhibitor; immune checkpoint inhibitor; plant growth regulator; structure determination.Formula: C5H8O3.
A novel compound, (R)-4-ethoxy-2-hydroxy-4-oxobutanoic acid (), and six known compounds (-) were isolated from the fruiting bodies of the wild edible mushroom Leucopaxillus giganteus. The planar structure of was determined by the interpretation of spectroscopic data anal. The absolute configuration of was determined by comparing sp. rotation of the synthetic compounds In the plant regulatory assay, the isolated compounds (-) and the chem. prepared compounds (-) were evaluated their biol. activity against the lettuce (Lactuca sativa) growth. Compounds and – showed the significant regulatory activity of lettuce growth. showed the strongest inhibition activity among the all the compounds tested. In the lung cancer assay, all the compounds were assessed the mRNA expression of Axl and immune checkpoints (PD-L1, PD-L2) in the human A549 alveolar epithelial cell line by RT-PCR. Compounds – showed significant inhibition activity against Axl and/or immune checkpoint.
In some applications, this compound(32780-06-6)Formula: C5H8O3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI