Final Thoughts on Chemistry for 32780-06-6

Different reactions of this compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Synthetic Route of C5H8O3 require different conditions, so the reaction conditions are very important.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called A useful method for the synthesis of β-2′,3′-dideoxynucleosides via a thioglycoside, published in 1992-07-31, which mentions a compound: 32780-06-6, Name is (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, Molecular C5H8O3, Synthetic Route of C5H8O3.

A series of the protected β-2′,3′-dideoxypyrimidine nucleosides is synthesized stereoselectively by the coupling of Ph 5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-1-thio-D-glycero-pentofuranoside (I) with silyl derivatives of nucleoside bases in the presence of NBS at -78°. Thus, I was treated with bis(trimethylsilyl)thymine in CH2Cl2 in the presence of 4A mol. sieves and NBS at -78° to give 83% a mixture of β- and α-dideoxynucleosides II and III in the ratio of 3.7:1 resp.

Different reactions of this compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Synthetic Route of C5H8O3 require different conditions, so the reaction conditions are very important.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI