So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Jaison, D.; Chandrasekaran, Gopalakrishnan; Mothilal, M. researched the compound: 5,6-Dihydro-2H-pyran-2-one( cas:3393-45-1 ).Safety of 5,6-Dihydro-2H-pyran-2-one.They published the article 《pH-sensitive natural almond gum hydrocolloid based magnetic nanocomposites for theragnostic applications》 about this compound( cas:3393-45-1 ) in International Journal of Biological Macromolecules. Keywords: iron oxide gum hydrocolloid magnetic nanocomposite theragnostic application; Almond gum; Anti-solvent; Natural hydrocolloids; pH responsive; γFe(2)O(3). We’ll tell you more about this compound (cas:3393-45-1).
In this study, iron oxide (γFe2O3) nanoparticles synthesized via hydrothermal route and doxorubicin (Dox) were successfully encapsulated into natural almond gum hydrocolloids via antisolvent precipitation technique. Cubic γFe2O3 crystal structure of the synthesized iron oxide nanoparticles were confirmed using X-ray diffraction and XPS. The refinement of XRD and elemental anal. revealed oxygen vacancies, which is also indicated by an increased magnetization comparable to bulk γFe2O3. Magnetization studies revealed the superparamagnetic nature of IO and IODPC nanoparticles. The particles were characterized for its morphol. (TEM and FESEM), size (FESEM, DLS), surface charge (DLS) and MRI (proton relaxation). The heating ability of the IO and IODPC nanoparticles was studied and their specific absorption rate was found to be 83.06 W/g and 154.37 W/g resp. The entrapment efficiency of the IODPC nanoparticles was found to be 88.29%. The drug release studies revealed that IODPC nanoparticles were more responsive towards acidic pH and their release follows Higuchi diffusion kinetics. In-vitro uptake and in-vitro cell viability studies were performed for IODPC nanoparticles using HeLA cell lines.
In some applications, this compound(3393-45-1)Safety of 5,6-Dihydro-2H-pyran-2-one is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI