Derivation of elementary reaction about 494-52-0

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Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 494-52-0, is researched, SMILESS is C1(C=NC=CC=1)[C@@H]1CCCCN1, Molecular C10H14N2Journal, Russian Journal of General Chemistry called Synthesis, Structure, and Biological Activity of Cinnamoyl-Containing Cytisine and Anabasine Alkaloids Derivatives, Author is Nurkenov, O. A.; Nurmaganbetov, Zh. S.; Seilkhanov, T. M.; Fazylov, S. D.; Satpayeva, Zh. B.; Turdybekov, K. M.; Talipov, S. A.; Seydakhmetova, R. B., the main research direction is cytisine cinnamoyl derivative preparation antibacterial antifungal cytotoxic activity; anabasine cinnamoyl derivative preparation antibacterial antifungal activity cytotoxic.Application In Synthesis of (S)-3-(Piperidin-2-yl)pyridine.

The reactions of the cytisine and anabasine alkaloids with cinnamic acid chloride have been studied, and hydrazinolysis of the resulting N-cinnamoylcytisine and N-cinnamoylanabazine has been carried out. The reaction of cinnamoyl isothiocyanate with alkaloids has afforded the corresponding thiourea derivatives Antimicrobial and cytotoxic activity of cinnamoyl-containing derivatives of these alkaloids has been evaluated.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI