Synthetic Route of C5H8O3. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about A facile and highly chemoselective protection of primary hydroxyl groups with 2-methyl-1-butene. Author is Figadere, Bruno; Franck, Xavier; Cave, Andre.
The chemoselective formation of tert-amyl ethers of primary hydroxyl groups in the presence of secondary hydroxyl groups is described. Thus, treatment of BuCH(OH)CH2OH with 1 equiv 2-methyl-1-butene in the presence BF3.Et2O afforded 78% BuCH(OH)CH2OCMe2Et and < 3% bis-tert-amyl ether. Compounds in my other articles are similar to this one((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Synthetic Route of C5H8O3, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI