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The surface-functionalization of poly(ethylene terephthalate) track-etched membranes of different nominal pore sizes (400, 1000 and 3000. nm) with stimuli-responsive poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) via surface-initiated (SI) atom transfer radical polymerization (ATRP) was performed. Variations of grafting density and grafted chain length were achieved by variation of synthesis conditions. It could be clearly demonstrated that mixtures of reaction solutions containing different ratios of acyl bromides, only one bearing the initiator group necessary for the SI ATRP, led to different initiator group densities on the resulting track-etched membrane surface which had been verified by X-ray photoelectron spectroscopy. Moreover the mass increase as function of reaction time strongly correlated with the amount of initiator bound to the membrane surface indicating that the ATRP reaction was not limited by monomer diffusion into the pores. Scanning electron microscopy images and permporometry measurements indicated an even functionalization on the entire membrane surface which was the basis for further investigations. The stimuli-responsive properties of PDMAEMA grafted track-etched membranes were studied by permeability measurements with citrate and glycine buffers as function of pH (2 and 10) and temperature (25 and 60 C). By that the barrier properties of the membranes could be effectively changed in two steps. The results agree with the expectation that a change in grafting density and chain length has an effect on the stimuli-responsive properties of the membrane. Results for membranes having similar degrees of grafting clearly showed that the reversible swelling of grafted polymeric layers was more pronounced for lower grafting density.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORgammat activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C9H23N3. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 3030-47-5

A series of light responsive linear-dendritic BCs consisting of a liquid crystalline aliphatic polyester dendron functionalized with sixteen 4-cyanoazobenzene moieties linked to a linear block of poly(methyl methacrylate), poly(ethyl methacrylate) or poly(styrene) have been investigated. The linear block was synthesis by atom transfer radical polymerization using an alkyne terminated initiator and was coupled to dendron with an azido group at the focal point by a Huisgen’s 1,3-dipolar cycloaddition. The effectiveness of the coupling reaction and purity of the block copolymers was asserted by chromatographic and spectroscopic techniques as well as their thermal behaviour was studied by thermogravimetric analysis, differential scanning calorimetry and optical microscopy. Morphology, optical properties and photoinduced response of these block copolymers have also been evaluated.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 3030-47-5, molcular formula is C9H23N3, introducing its new discovery. Recommanded Product: 3030-47-5

Isocyanate-functional silanes, particularly isocyanate-functional alpha-silanes, are prepared in good yield by a liquid phase thermolysis conducted in the presence of a catalyst at a pressure of >100 mbar, or >80 mbar when a thin-film evaporator is used.

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Metal catalyst and ligand design,
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The synthesis of a series of short poly(norbornene)s displaying pendant disaccharides is reported. para-(Propargyloxy)benzyl moieties were attached to a norbornenyl group via an ester or amide linkage, giving two different pre-monomers. A set of protected beta-(1?6)-linked glucosamine-based disaccharides, structurally similar to the bacterial biofilm constituent poly-N-acetylglucosamine (PNAG), were attached to the pre-monomers via a Huisgen 1,3-dipolar cycloaddition reaction to generate a series of ‘glycomonomers’. In the presence of a Grubbs’ 3rd generation catalyst, the glycomonomers displayed variable reactivities that were dependent on the type of linkage (ester or amide) between the norbornenyl and benzyl moieties. In general, the amide-linked glycomonomers polymerized at a much slower rate and had a comparatively lower degree of polymerization than the corresponding ester-linked constructs. All the materials displayed a relatively narrow molecular weight distribution ( = 1.2-1.5).

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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A novel biphasic solvent consisting of diethylenetriamine (DETA), 2-amino-2-methyl-1-propanol (AMP), and pentamethyldiethylenetriamine (PMDETA) is considered as a promising CO2-capturing candidate because of its high absorption capacity, favorable phase separation behavior, fast desorption rate, and high cyclic capacity. In the present work, reaction kinetics and thermodynamics of CO2 absorption into the DETA-AMP-PMDETA biphasic solvent were studied. The kinetics process of CO2 absorption was described using the zwitterion mechanism and invoking the two-film theory. Under the fast pseudo-first-order regime, kinetics parameters, e.g., overall reaction rate constant (kov,mix), second-order rate constant (k2,mix), and enhancement factor (E), were determined. Kinetics results indicated that the CO2 reaction rate was mainly determined by DETA and AMP in the biphasic system, while PMDETA molecules would aggregate to form PMDETA clusters, which limited the absorption of CO2 to a certain extent. On the other hand, thermodynamics results showed that the regeneration heat of DETA-AMP-PMDETA biphasic solvents could be significantly reduced compared with that of MEA. In particular, the regeneration heat of the solvent 0.5 mol·L-1 (M) DETA + 1.5 M AMP + 3 M PMDETA (0.5D1.5A3P) was only 1.83 GJ·ton-1 CO2, which was approximately 52% lower than that of 30 wt % MEA. This finding suggested that the DETA-AMP-PMDETA biphasic solvent may be a good alternative to MEA to advance energy-efficient and economical CO2 capture.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Through the incorporation of chiral and achiral poly(3-alkylthiophenes) (P3ATs) into a star-shaped system, a well-defined supramolecular organization is obtained lacking the unfavorable linear lamellar structure typically obtained for P3AT. Through the combination of a controlled chain-growth polymerization and efficient postpolymerization and click reactions, well-defined star-shaped P3ATs with a low dispersity of 1.1 were obtained. The combination of UV-vis, circular dichroism (CD), atomic force microscopy (AFM), and transmission electron microscopy (TEM) measurements showed the formation of a strong (chiral) supramolecular organization into fibers, different and stronger than those obtained with the linear P3ATs. The fact that the width of the fibers is in good agreement with the width of a single star-shaped P3AT excludes the formation of a linear lamellar structure. Furthermore, the particular supramolecular organization of the star-shaped polymers, which appears thanks to the precision polymer synthesis, triggers properties of the arms of the star-shaped molecule that are not present in the individual arms.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 3030-47-5, name is N1-(2-(Dimethylamino)ethyl)-N1,N2,N2-trimethylethane-1,2-diamine, introducing its new discovery. Computed Properties of C9H23N3

(CDT)NiCO (2), a thermally instable complex previously obtained only in solution, has been isolated and its chemical and spectroscopic properties investigated.The formation of this compound from various different (CDT)NiL complexes suggests that thermodynamically it is relatively stable.Although the CDT can be displaced by other ligands, the carbon monoxide in (CDT)NiCO (2) is not liberated. – On reaction with strong nucleophiles such as lithiumorganyls and -amides, the complexed CO in (CDT)NiCO can be converted to a lithiumacyl or -carbamoyl group.In the resulting (PMDTA)Li(OCR)Ni(CDT) (R = CH3, C6H5, NMe2) (3 – 5) the transition metal is, in addition to the acyl or carbamoyl residue, bound only to an olefin as stabilizing ligand.When R = Me or NMe2, these compounds react further with CO to form the carbonyl-containing lithiumacetyl or -carbamoyl complexes (PMDTA)Li(OCR)Ni(CO)3 (R = Me or NMe2) (6, 7a).Complexes of this type can be prepared from Ni(CO)4 directly only if R = NMe2.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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The release of persistent and mobile organic chemicals (PMOCs) into the aquatic environment puts the quality of water resources at risk. PMOCs are challenging to analyze in water samples, due to their high polarity. The aim of this study was to develop novel analytical methods for PMOCs and to investigate their occurrence in surface and groundwater samples. The target compounds were culled from a prioritized list of industrial chemicals that were modeled to be persistent, mobile, and emitted into the environment. Analytical screening methods based on mixed-mode liquid chromatography (LC), hydrophilic interaction LC, reversed phase LC, or supercritical fluid chromatography in combination with mass spectrometric detection were successfully developed for 57 target PMOCs and applied to 14 water samples from three European countries. A total of 43 PMOCs were detected in at least one sample, among them 23 PMOCs that have not been reported before to occur in environmental waters. The most prevalent of these novel PMOCs were methyl sulfate, 2-acrylamino-2-methylpropane sulfonate, benzyltrimethylammonium, benzyldimethylamine, trifluoromethanesulfonic acid, 6-methyl-1,3,5-triazine-diamine, and 1,3-di-o-tolylguanidine occurring in ?50% of the samples at estimated concentrations in the low ng L?1 up to mug L?1 range. The approach of focused prioritization combined with sensitive target chemical analysis proved to be highly efficient in revealing a large suite of novel as well as scarcely investigated PMOCs in surface and groundwater.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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We introduced a small molecular “inducing ligand” strategy to crystallize proteins via dual noncovalent interactions. Here we demonstrate that the variant protein-packing frameworks of concanavalin A (ConA) binding with ligands are controlled by different crystallization methods. Besides, the protein crystalline frameworks are also controlled by small-molecule inducing ligands RnM (n = 1-5), which varies in the number of ethylene oxide repeating units. To better understand the mechanism of different packing frameworks controlled by different inducing ligands, all-atom molecular dynamic (MD) simulations were performed. The MD simulation focused on the dynamic dimerization behavior of ConA-RnM system, which revealed clear relationships between the length of inducing ligands and ConA crystalline. In short, besides protein-packing framework control via different crystallization methods, inducing ligands RnM with suitable spacer lengths (n = 3, 4) also play an important role in desired and stable crystalline frameworks.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI