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(equation presented) The first enantioselective ruthenium olefin metathesis catalysts have been prepared, and high enantiomeric excesses (up to 90%) are observed in the desymmetrization of achiral trienes. A model consistent with the stereochemical outcome of the reactions is described and suggests side-on olefin binding and reorganization of the halide ligands.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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New water-soluble rhodium and iridium complexes of 2,2′-bipyridines, functionalized with PO3Na2 groups, show very good catalytic activities in the reduction of various substituted acetophenones under hydrogen pressure in basic aqueous media. No significant loss of catalyst activity is observed after one use.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Novel unsymmetrical salan fluorescent sensors 2a and 2b have been designed and synthesized. The chiral recognition of N-Boc-protected amino acids by 2a and 2b has been investigated. Sensor 2a possesses higher sensitivity and enantioselectivity than sensor 2b does. Job analysis and nonlinear regression results show that 2a can form a 1:1 stoichiometric complex with a N-Boc-protected amino acid. The obtained response selectivities and the association constants indicate that 2a is a highly enantioselective and sensitive fluorescent sensor toward N-Boc-protected amino acids.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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A novel class of peptide nucleic acid monomers are synthesized having chirality in the backbone. Peptide nucleic acid oligomers are synthesized to incorporate these chiral monomers.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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A new class of chiral C2-symmetrical diamino-oligothiophenes is described to be effective in catalyzing Pd-mediated asymmetric allylic alkylations in a highly enantioselective manner. The combination of experimental as well as crystallographic evidence revealed the key role played by sulfur-based heteroaromatic rings in the stereodiscriminating step of the procedure. In particular, unprecedented non-covalent secondary interactions between the inner thiophene and the metal center proved to be essential to create the stereochemical environment necessary in order to guarantee excellent levels of chemical and optical yields.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C6H14N2. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 20439-47-8

A new strategy for the immobilization of iminium organocatalysts through, the acid-base assembly of multidentate chiral primary amines and solid polyacids is presented, A suitable structurally distinctive C2-symmetric chiral primary amine (CPA) was identified in this study and the optimal CPA-POM hybrid obtained catalyzed the Diels-Alder cycloaddition of a-substituted acroleins in high yields and fair-to-high selectivity under aqueous conditions. The primary amine in the metal-organic-framework (MOF)-like catalyst acted as the catalytic center as well as multidentate basic centers, whereas phosphotungstic acid played dual roles as both catalyst anchors and modulators of the activity and stereoselectivity, Furthermore, the MOF-like catalyst showed both high reactivity and physical stability and thus could be recycled and reused six. times with only a small loss of activity and selectivity.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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A benign and efficient synthesis of chiral macrocyclic ‘aza-crown’ ethers of varying ring size is reported. The synthesis involves a Schiff base condensation of ether linked dialdehydes of varying chain length and (1R,2R)-(-)-1,2-diaminocyclohexane under mild conditions to yield the macrocycles, which are subsequently reduced to yield the diamino analogues.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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The synthesis of several chiral tropocoronands (6 and 7) has been accomplished. These compounds have been shown to complex with various metals. Tropocoronands that have been synthesized include H2(TC-3,cyhex) through H2(TC-6,cyhex) (6) and H2 (TC-3,diphen) through H2(TC-6,diphen) (7). The route is short and the tropocoronands are easily purified by chromatography or recrystallization. Two other groups have been incorporated into tropocoronands, H2(TC-3,binap) (9) and H2(TC-6,pent) (10).

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Metal-organic cages (MOCs) are a novel kind of porous materials which have three dimensional structures with perpetual and well-defined holes. They have attracted wide consideration for relatively simple synthesis and potential applications such as separation, sensing, microreactor and catalysis etc. In this study, a homochiral MOC [Zn3L2] was prepared as a novel stereoselective stationary phase and added into poly (ionic liquid-co-ethylene dimethacrylate) (Zn3L2@poly(IL-co-EDMA)) monolith for capillary electrochromatography (CEC). The chiral analytes comprising mandelic acid, benzoin and furoin enantiomer were separated perfectly using the monolithic column Zn3L2@poly(IL-co-EDMA), and the effects of buffer pH, acetonitrile percentage and buffer concentration on enantiomers separation were confirmed. Moreover, incorporation of MOC [Zn3L2] into IL polymer monolith strengthened obviously the stereoselective isolation of some positional isomers (such as nitrophenols, nitrotoluenes, xylenes, and ionones). The relative standard deviations (RSDs) of the retention time for intra-day (n = 5) and inter-day (n = 3) and column-to-column (n = 3) enantioseparations were all below 5.0%. This novel monolithic column combined distinct features of the stereoselective materials with the eminent traits of ionic liquid matrix, it has great application potential in CEC.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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New chiral Schiff base complexes have been obtained by condensation of 2,2?-diamino-1,1?-binaphthalene or 1,2-diaminocyclohexane and various salicylaldehydes and by subsequent metalation with manganese, iron, cobalt, nickel, copper, or zinc. The complete 1H and 13C NMR characterization of the ligands is reported, as are the X-ray crystal structures of (1R,2R)-(-)-N,N’-bis[3-(N,N-dimethylamino)salicylidene]-trans-1,2- cyclohexanediimine and [(1R,2R)-(-)-N,N’-bis(salicylidene)-trans-1,2-cyclohexanediiminato]copper(II). The new chiral manganese complexes have been evaluated in the oxygenation of prochiral olefins and sulfides using sodium hypochlorite, hydrogen peroxide, or N-methylmorpholine N-oxide/m-chloroperbenzoic acid as oxidant.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI