168646-54-6 | Page 2 of 2 | Catalyst ligands

Brief introduction of 168646-54-6

168646-54-6, 168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various fields.

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: [Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to adichloromethane (DCM) solution (about 12 mL) of dap (21.4 mg,98percent, 0.100 mmol) and xantphos (59.0 mg, 98percent, 0.100 mmol) undera stream of dry argon by using Schlenk techniques at room temperatureand a vacuum-line system, then orange-red solutionwas obtained quickly and stirred for 1 h at room temperature.The above process can also be carried out in air with the existenceof oxygen. After filtration through absorbent cotton, layeringn-hexane onto the filtrate in air produced the product as orangeredcrystals in 35?44percent yield (39.1?49.3 mg).

168646-54-6, 168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Yao, Xi-Xi; Guo, Ya-Meng; Liu, Rong; Feng, Xiao-Yan; Li, Hao-Huai; Liu, Nian; Yang, Feng-Lei; Li, Xiu-Ling; Polyhedron; vol. 92; (2015); p. 84 – 92;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Some tips on 168646-54-6

168646-54-6, As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

1) Under a nitrogen atmosphere,4,4′-dimethyldiphenylamine (1.97 g, 10 mmol)CuI (28.5 mg, 0.15 mmol),1,10-phenanthroline (54 mg, 0.3 mmol)Potassium hydroxide (1.12 g, 15 mmol),2-iodo-dithiophene (3.16 g, 12 mmol),Water (7 mL) and xylene (20 mL)The reaction was carried out at 130 ¡ã C for 24 hours,The reaction mixture was poured into methylene chloride (100 mL), washed with water, and the organic phase was collected and dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure and the residue was passed through a silica gel column. The mobile phase was a 1: 3 by volume mixture of dichloromethane and petroleum ether to give intermediate P3;2)The intermediate P3 (3.35 g, 10 mmol) was dissolved in dry dichloromethane (50 mL)Anhydrous aluminum trichloride (1.6 g, 12 mmol) was added portionwise at 0 ¡ã C,After stirring for 20 minutes,A solution of oxalyl chloride (5 mmol) in dichloromethane (10 mL) was slowly added dropwise,Drop finished, rose to room temperature to continue stirring 6 hours, the reaction completed,A 10percent aqueous hydrochloric acid solution (10 mL) was added dropwise to the reaction solution,The organic phases were collected, washed with saturated sodium bicarbonate solution and water, dried over anhydrous sodium sulfate,The solvent was distilled off under reduced pressure,The residue was passed through a silica gel column and the mobile phase was a 1: 1 by volume mixture of dichloromethane and petroleum ether to give intermediate P4;3) 5,6-diamino-1, 10-phenanthroline A (2.10 g, 10 mmol)Intermediate P4 (10 mmol) and glacial acetic acid (40 mL) were refluxed at 120 & lt; 0 & gt; C for 24 hours,Down to room temperature,The solvent was distilled off under reduced pressure,The residue was extracted with chloroform,Washed with 10percent sodium bicarbonate solution and saturated brine, respectively,Dried over anhydrous sodium sulfate.The solvent was distilled off under reduced pressure, the residue was passed through a silica gel column,The mobile phase is a 1: 1 by volume mixture of methylene chloride and ethyl acetate,The organic photosensitive dye D2, the yield of 56percent

168646-54-6, As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Reference£º
Patent; China Academy of Sciences Huaxue Academe; Zhang, Lipeng; Fan, Xinheng; Chen, Qiang; Jiang, Kejian; Yang, Lianming; (14 pag.)CN104672237; (2017); B;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Downstream synthetic route of 168646-54-6

168646-54-6, The synthetic route of 168646-54-6 has been constantly updated, and we look forward to future research findings.

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

5,6-Diamino-1,10-phenanthroline was synthesized according to the literature [40]. 5,6-diamino-1,10-phenanthroline (1.20 mmol, 0.25 g) and furoin (1.20 mmol, 0.23 g) were dissolved in 20.0 mL of dimethyl formamide. The mixture was refluxed for 2 days under the atmosphere of nitrogen. dpq-df was collected via filtration and recrystallization by DMF. Yield: 0.25 g, 57percent. 1H NMR [(CD3)2SO]: delta 9.43 (2H, d, J = 8.3 Hz), 9.25 (2H, d, J = 4.8 Hz), 7.98 (4H, m, J = 18.3 Hz), 7.11 (2H, d, J = 3.2 Hz), 6.82 (2H, d, J = 4.7 Hz). Anal. data for C22N4H12O2: calc. (percent): C, 72.52; H, 3.32; N, 15.38. found (percent): C, 72.56; H, 3.31; N, 15.43.

168646-54-6, The synthetic route of 168646-54-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Lu, Xiao-Hui; Shi, Shuo; Yao, Jun-Liang; Gao, Xing; Huang, Hai-Liang; Yao, Tian-Ming; Journal of Inorganic Biochemistry; vol. 140; (2014); p. 64 – 71;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Simple exploration of 168646-54-6

As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to adichloromethane (DCM) solution (about 12 mL) of dap (21.4 mg,98percent, 0.100 mmol) and xantphos (59.0 mg, 98percent, 0.100 mmol) undera stream of dry argon by using Schlenk techniques at room temperatureand a vacuum-line system, then orange-red solutionwas obtained quickly and stirred for 1 h at room temperature.The above process can also be carried out in air with the existenceof oxygen. After filtration through absorbent cotton, layeringn-hexane onto the filtrate in air produced the product as orangeredcrystals in 35?44percent yield (39.1?49.3 mg). Anal. Calc. forC52H44Cl3CuN4O5P2 (1aCH2Cl2): C, 60.34; H, 4.29; N, 5.42. Found:C, 60.01; H, 4.34; N, 5.45percent. ESI-MS (m/z): 851.214[Cu(dap)(xantphos)]+ (calcd 851.212); 641.123 [Cu(xantphos)]+(calcd 641.122). 1H NMR (400 MHz, DMSO-d6, delta, ppm): 8.681 (d,2H, J = 8.4 Hz), 8.209 (d, 2H, J = 4.4 Hz), 7.852 (dd, 2H, J = 7.6 Hz,J0 = 1.2 Hz), 7.650 (dd, 2H, J = 8.4 Hz, J0 = 4.4 Hz), 7.252 (t, 6H,J = 7.6 Hz), 7.102 (t, 8H, J = 7.6 Hz), 6.888?6.844 (m, 8H), 6.476?6.438 (m, 2H), 5.758 (s, 2H, CH2Cl2), 5.638 (s, 4H, NH2), 1.745 (s,6H, CH3). 31P{1H} NMR (400 MHz, DMSO-d6, delta, ppm): 13.097.Characteristic IR spectrum (KBr, cm-1): 3444m (NH2), 3372m(NH2), 2969m (CH3), 2925w (CH3), 1101vs (ClO4).

As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Brief introduction of 168646-54-6

168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various.

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The reaction and workup steps were performed air-free using standard Schlenk technique or by carrying out manipulations in a N2-filled glovebox. Compound 46 (43 mg, 0.2045 mmol, 1 eq) and Re(CO)5Cl (74 mg, 0.2045 mmol, 1 eq) were suspended in 30 rriL of toluene. The mixture was refluxed for 18 h and then cooled to RT followed by further cooling in an 8 ¡ãC fridge for 30 min. The precipitate was isolated via filtration and washed with hexane to obtain analytically pure product in 88percent yield. 1H-NMR (400 MHz, DMSO-d6) delta (ppm): 9.07 (dd, 2H), 8.90 (dd, 2H), 7.91 (dd, 2H), 5.82(s, 4H). 13C-NMR(150.9 MHz, DMSO-d6) 5 (ppm): 198.15, 190.39, 148.49, 140.17, 132.02, 124.81, 123.90, 123.57. ATR-IR(cm_1): 3460(w), 3412(w), 3363(w), 3298(w), 2020(s), 1930(s), 1895(s), 1664(m), 1617(m), 1589(m), 1489(m), 1436(m) Anal. Calcd for Ci5H10N4O3ReCl: C, 34.92; H, 1.95; N, 10.86. Found: C, 35.05; H, 1.82; N, 10.25.

168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various.

Reference£º
Patent; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; SURENDRANATH, Yogesh; FUKUSHIMA, Tomohiro; O’REILLY, Matthew, E.; OH, Seokjoon; MURRAY, Alexander T.; KAMINSKY, Corey Jarin; CHU, Sterling Ben; JACKSON, Megan N.; (161 pag.)WO2017/31050; (2017); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI