Category: 1662-01-7

1662-01-7, 4,7-Diphenyl-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Preparation of the [Ir(C^N)2(N^N)]3+[PF6-]3: in typical reaction procedure 0.10 g (0.058 mmol) of [{Ir(C^N)2Cl}2]4+[PF6]4, 0.04 g (0.16 mmol) AgPF6 and 0.03-0.06 g (0.19 mmol) of N^N ligand were heated at 100 C under argon in 15 ml of argon-purged 2-methoxyethanol/water mixture (8:2 v/v) for ca. 36 h. After cooling, the reaction mixture to ambient temperature, the precipitated AgCl was filtered off and the solvents were removed by rotary evaporation. The residue was dissolved in small amount of acetone and an excess of [NnBu4]Cl was added. The precipitate was filtered off and washed with acetone. The hexafluorophosphate salts were further obtained by anion metathesis with NH4PF6 in cold water with yields: [Ir(C^N)2(phen)]3+[PF6-]3 64%, [Ir(C^N)2(tmphen)]3+[PF6-]3 81%, [Ir(C^N)2(dpphen)]3+[PF6-]3 53%, [Ir(C^N)2(dpq)]3+[PF6-]3 42%, [Ir(C^N)2(dppz)]3+[PF6-]3 39%, [Ir(C^N)2(dppn)]3+[PF6-]3 57%. For the NMR data see Supporting information.

1662-01-7, The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kamecka, Anna; Grochowska, Olga; Kapturkiewicz, Andrzej; Inorganic Chemistry Communications; vol. 108; (2019);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

(28A) tert-Butyl{3-[4-(3,4-dichlorobenzyloxy)phenyl]-3-vinyloxypropoxy}dimethylsilane3-(tert-Butyldimethylsilyloxy)-1-[4-(3,4-dichlorobenzyloxy)phenyl]propan-1-ol (300 mg, 0.680 mmol) produced in Example 27 (27B), palladium(II) trifluoroacetate (12 mg, 0.036 mmol), and 4,7-diphenyl-1,10-phenanthroline (12 mg, 0.036 mmol) were dissolved in butyl vinyl ether (5 mL), and triethylamine (20 muL, 0.14 mmol) was added thereto, and the resulting mixture was stirred under a nitrogen atmosphere at 80 C. for 4 hours. After cooling to room temperature, the reaction solution was filtered, and the solvent was distilled off under reduced pressure, whereby a crude product was obtained. This crude product was purified by silica gel column chromatography (hexane:ethyl acetate=100:0 to 96:4 (v/v)), whereby the objective title compound was obtained as a colorless oily substance (275 mg, yield: 87%).1H NMR (CDCl3, 400 MHz): delta0.04 (3H, s), 0.05 (3H, s), 0.91 (9H, s), 1.85 (1H, m), 2.07 (1H, m), 3.41 (1H, m), 3.57 (1H, m), 3.95 (1H, dd, J=1.6, 6.6 Hz), 4.23 (1H, dd, J=1.6, 14.1 Hz), 4.90 (1H, dd, J=5.1, 8.2 Hz), 5.00 (2H, s), 6.29 (1H, dd, J=6.6, 14.1 Hz), 6.92 (2H, d, J=9.0 Hz), 7.22 (2H, d, J=9.0 Hz), 7.24-7.28 (2H, m), 7.45 (1H, d, J=8.6 Hz), 7.54 (1H, d, J=2.0 Hz)

1662-01-7, 1662-01-7 4,7-Diphenyl-1,10-phenanthroline 72812, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; DAIICHI SANKYO COMPANY, LIMITED; US2011/53974; (2011); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: A solution of [Rh2Cl2(COD)2] (0.1mmol), 1,10-phenanthroline (0.2mmol) and HBF4 (0.025ml, 40% water solution) in 5mL of ethanol was stirred at room temperature for 18h. The red-orange product was filtrated off, washed with ethanol and dried under vacuum., 1662-01-7

1662-01-7 4,7-Diphenyl-1,10-phenanthroline 72812, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; ?liwi?ska-Hill, Urszula; Pruchnik, Florian P.; Latocha, Ma?gorzata; Nawrocka-Musia?, Dominika; U?aszewski, Stanis?aw; Inorganica Chimica Acta; vol. 400; (2013); p. 26 – 31;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: The preparation of the homologous series of osmium complexes with alpha diimineligands was modified from previous literature methods [5]. The precursor Os(L)2Cl2 was synthesized by refluxing ammonium hexachloroosmate in a 1:2 M ratio with L = 2,2?-bipyridine (bpy), 1,10-phenanthroline (phen), or bathophenanthroline (dpp) in 10 mL of ethylene glycol under nitrogen for 45 min. After cooling to room temperature, sodiumhydrosulfite (0.17 M) was added to reduce the osmium from Os(IV) to Os(II). Precipitation of Os(bpy)2Cl2,Os(phen)2Cl2, and Os(dpp)2Cl2 was achieved via an ice-bath,and the solid was washed with deionized water and ethylether. Yields were close to 80 %.

1662-01-7, The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Wagner, Amy M.; Strohecker, Sarah A.; Costello, Elizabeth K.; Rood, Jeffrey A.; Kneas, Kristi A.; Journal of Fluorescence; vol. 26; 6; (2016); p. 2271 – 2280;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

(Cmpd 11): 4,7-Diphenyl-2-(2-pyridyl)-1,10-phenanthroline. n-Butyllithium (18.8 ml of a 1.6 M solution in hexane, 0.03 mol) is added under argon to a cold (-78C) tetrahydrofurane (100 ml). 2-Bromopyridine (4.75 g, 0.03 mol) is then added during 15 minutes while keeping the temperature at -78 C. The brown solution is stirred 50 minutes at -78C, thereafter finely powdered 4,7-diphenyl-1,10-phenanthroline (6.64g, 0.02 mol) is added and the mixture is allowed to warm to room temperature during 2 h. Methanol (20 ml) is then added and the brown solution is evaporated on a rotary evaporator. The residue is dissolved in dichloromethane (300 ml) and methanol (10 ml), manganese dioxide (30 g) is added and the mixture is stirred at room temperature 12 h. The solids are removed by filtration, the filtrate is evaporated and the residue is chromatographed on silica gel with dichloromethane-2-propanol (9:1). The pure fractions are crystallized from dichloromethane-ethanol to afford 2.12 g of the title compound. Light yellow, microcrystalline powder, mp (DSC in air, scan rate 10Cmin-1) = 227.8-233.7C. 1H-NMR (300 MHz, CD3Cl): 9.32 (d, J=4.8 Hz, 1H), 9.07 (d, J=7.8 Hz, 1H), 8.80 (s, 1H), 8.73 (d, J=6.3 Hz, 1H), 7.99-7.85 (m, 3H), 7.63-7.36 (m, 12H). MS for C29H19N3 (409.49) found M=409.69., 1662-01-7

As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

Reference£º
Patent; BASF SE; EP2161272; (2010); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: To a solution of 2-phenyl-3-hydroxy-4(1H)-quinolinone (237 mg, 1 mmol) in ethanol (50 mL), the corresponding bidentate N-donor ligand (L) (1 mmol) dispersed in EtOH (5 mL) was added while stirring. To this mixture, a solution of Cu(BF4)2¡¤H2O (237 mg, 1 mmol) in H2O (5 mL) was slowly added while stirring. The reaction mixture was stirred at room temperature for a few hours, and subsequently left to stand for several days at room temperature. The obtained solid product was filtered off, washed with a small amount of cold water and ethanol, and dried in the air at 40 C., 1662-01-7

The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Buchtik, Roman; Travnicek, Zdenek; Vanco, Jan; Journal of Inorganic Biochemistry; vol. 116; (2012); p. 163 – 171;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1662-01-7, 4,7-Diphenyl-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of [Pt2Me4(mu-SMe2)2] (51mg, 0.09mmol) in acetone (5mL) was added a solution of bphen (59mg, 0.18mmol) in acetone (30mL). The reaction color changed to deep red and the solution stirred for 2h at room temperature. After removal of the solvent under reduced pressure, the dark red complex was obtained and air dried. Yield: 72%; m.p. 221C (dec). Anal. Calc. for C26H22N2Pt: C, 56.01; H, 3.98; N, 5.02. Found: C, 55.67; H, 4.27; N, 4.77%. NMR data in CDCl3: delta(1H) 1.30 [s, 6H, 2J(Pt-H)=85.3Hz, Pt-Me], 7.56 [s, 10H, Ph groups], 7.75 [d, 2H, 3J(HH)=5.1Hz, H3], 7.94 [s, 2H, H5], 9.56 [d, 2H, 3J(HH)=5.1Hz, 3J(Pt-H)=25.4Hz, H2]; delta(13C)-17.1 [s, 1J(Pt-C)=804Hz, Pt-Me], 125.2 (C5), 126.1 [C3, 2J(Pt-C)=19Hz], 128.8 (C1), 129.2-129.4 (Ph groups), 137.1 (C13), 146.4 [C2, 2J(Pt-C)=33Hz], 148.6 (C11), 148.8 (C4); delta(195Pt)-3359. UV-Vis (lambdamax in toluene): 474 and 516nm.

1662-01-7, As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

Reference£º
Article; Momeni, Badri Z.; Fathi, Nastaran; Moghadasi, Milad; Biglari, Abbas; Janczak, Jan; Journal of Organometallic Chemistry; vol. 880; (2019); p. 368 – 377;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1662-01-7, 4,7-Diphenyl-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1662-01-7, General procedure: The formerly reported protocol for the preparation of complex Ru-Cl [1] was modified,as described below, and this modification was used also for the Os(II) analogue Os-Cl. Thestarting dimer [M(mu-Cl)(eta6-pcym)Cl]2 (0.10 mmol; M = Ru or Os) reacted with an excess (0.15mmol) of bphen in 5 mL of MeOH in a microwave reaction system (100 C, 1 min). Theobtained solutions were cooled to ambient temperature, and an excess of NH4PF6 (3.0 mmol)was added. The solvent volume was reduced after 15 min of stirring at ambient temperature,until the solid formed. The obtained chlorido complexes [Ru(eta6-pcym)(bphen)Cl]PF6 (Ru-Cl)and [Os(eta6-pcym)(bphen)Cl]PF6 (Os-Cl) were collected by filtration, washed (1 ¡Á 0.5 mL ofMeOH and 3 ¡Á 1 mL of diethyl ether) and dried under vacuum.

As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

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Article; Starha, Pavel; Travni?ek, Zden?k; Van?o, Jan; Dvo?ak, Zden?k; Molecules; vol. 23; 2; (2018);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1662-01-7, 4,7-Diphenyl-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Synthesis of 2,4,7-triphenyl-1,10-phenanthrolineTo a three-necked flask of 250 ml, 0.97 g (6.16 mmol) of bromobenzene and 70 ml of THF were charged, then 3.9 ml (22 mmol) n-butyllithium (1.6M in Hexane solution) was dropped under stirring at -78 C. in a nitrogen atmosphere. The mixture was stirred for one hour at -78 C., and a solution of 1.86 g (5.6 mmol) 4,7-diphenyl-1,10-phenanthroline in 30 ml THF was dropped. Then the mixture was stirred at room temperature for overnight and was added with water. The organic layer was extracted with Dichloromethane and dried with anhydrous magnesium sulfate, the solvent was removed by rotary evaporation. The product was purified by column chromatography on alumina using Dichloromethane/Hexane as eluent and dried in vacuo, obtaining white powder compound 0.85 g (yield of 37.21%).

1662-01-7, 1662-01-7 4,7-Diphenyl-1,10-phenanthroline 72812, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Yen, Feng Wen; US2008/265746; (2008); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

[CuI(MeCN)4](ClO4) (50mg, 0.15mmol), PPh3 (80.4mg, 0.30mmol) and Ph2Phen (55.9mg, 0.17mmol) in MeCN (15ml) are stirred at room temperature for 1h. Slow evaporation of a MeCN solution of 3 afforded analytically pure complex as yellow crystalline solid. Yield (93.1mg, 59.8%). Elemental analysis for C60H46ClCuN2O4P2: calcd. C 70.65, H 4.55, N 2.75%; found: C 70.60, H 4.70, N 2.77%. Selected IR (KBr, cm-1): v(Cl-O) 1111. ESI-MS (positive): m/z 919 (M+). 1H NMR (300MHz, CDCl3): delta 8.83 (d, J=5.0Hz, 2H, phen H); 8.01 (s, 2H, phen H); 7.74 (d, J=5.0Hz, 2H, phen H); 7.62 (m, 6H, phenyl H); 7.57-7.51 (m, 4H, phenyl H); 7.37 (m, 6H, phenyl H); 7.26-7.14 (m, 24H, phenyl H). 31P{1H} NMR (162MHz, CDCl3): delta 2.97 (s, PPh3). UV/Vis (CH3CN): lambdamax /nm (epsilon/mol-1dm3cm-1): 228 (71180), 285 (58210), 381 sh (5810).

1662-01-7, As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

Reference£º
Article; Hu, Lin-Li; Shen, Chang; Chu, Wing-Kin; Xiang, Jing; Yu, Fei; Xiang, Ge; Nie, Yan; Kwok, Chun-Leung; Leung, Chi-Fai; Ko, Chi-Chiu; Polyhedron; vol. 127; (2017); p. 203 – 211;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI