Chemistry is an experimental science, Formula: C5H9NO2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 344-25-2, Name is H-D-Pro-OH
Recently, ll-diaminopimelate aminotransferase (ll-DAP-AT), a pyridoxal-5?-phosphate (PLP)-dependent enzyme, was reported to catalyze a key step in the biosynthesis of l-lysine in plants and Chlamydia. Previous screening of a 29201-compound library against ll-DAP-AT identified an o-sulfonamidoarylhydrazide as a reversible inhibitor with IC50 ? 5 muM. Structure-activity relationship (SAR) studies based on this lead compound identified key structural features essential for enzyme inhibition and led to slightly improved inhibitors. Preliminary studies on the mode of inhibition of ll-DAP-AT by this class of compounds are also reported.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C5H9NO2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 344-25-2, in my other articles.
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI