With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7173-51-5,N-Decyl-N,N-dimethyldecan-1-aminium chloride,as a common compound, the synthetic route is as follows.,7173-51-5
General procedure: In a round-bottom flask equipped with dropping funnel and reflux condenser 0.01 mol of (4-chloro-2-methylphenoxy)acetic acid, 40 mL of distilled water and 0.011 mol of 10% aqueous solution of NaOH was heated at 50 C until the mixture became a clear solution. Then a stoichiometric amount of quaternary ammonium chloride was added and the mixture was stirred for 30 min at room temperature. The product deposited as the bottom layer, which was separated. Then it was dissolved in 50 mL of chloroform. The organic phase was washed with distilled water until no chloride was present in water. After removal of chloroform the product was dried under reduced pressure at 60 C for 24 h.
The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Pernak, Juliusz; Syguda, Anna; Janiszewska, Dominika; Materna, Katarzyna; Praczyk, Tadeusz; Tetrahedron; vol. 67; 26; (2011); p. 4838 – 4844;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI