Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 3393-45-1, is researched, Molecular C5H6O2, about Unified Total Synthesis of Five Bufadienolides, the main research direction is bufadienolide synthesis antitumor.Computed Properties of C5H6O2.
We report a unified total synthesis of five bufadienolides: bufalin, bufogenin B, bufotalin, vulgarobufotoxin, and 3-(N-succinyl argininyl) bufotalin. After the steroidal ABCD ring was produced, the D ring was cross-coupled with a 2-pyrone moiety and stereoselectively epoxidized. TMSOTf promoted a stereospecific 1,2-hydride shift to establish the β-oriented 2-pyrone. Functional group manipulations furnished the bufadienolides, which potently inhibited cancer cell growth.
In some applications, this compound(3393-45-1)Computed Properties of C5H6O2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI